At Leafy Tunnel, we are on a mission to dedicate ourselves to humanity’s quest for longer, healthier and happier lives by advancing a new class of alternative medicines with extraordinary therapeutic potential. Our investment in Maya Health is an excellent example of how we fulfil this mission.

Maya Health is a measurement-based care platform designed to support psychedelic practitioners and patients. Through several years of conversations with practitioners of all types, the Maya Health team learned about the importance of planning their patients’ journey from preparation and facilitation to integration and completion. Key challenges for practitioners are to measure patients’…


Empathogens or entactogens are a class of psychoactive drugs that produce experiences of emotional communion, oneness, relatedness, emotional openness. Most entactogens are phenethylamines with 3,4-methylenedioxymethamphetamine (the “MDMA”) as being a major substance of this chemical class.

MDMA acts in the brain through three main neurochemical mechanisms: blockade of serotonin reuptake, induction of serotonin release, and induction of dopamine release [1]. The key characteristic of MDMA is its ability to block and release serotonin at the same time, whilst most drugs such as Prozac and other antidepressants are only able to do one of these neurochemical mechanisms. Essentially, MDMA floods the…


Throughout history, cannabis has been perceived by many cultures and countries as something that only causes harm and destroys societies and people. This was seen from Nixon’s “War on Drugs” to many other political movements that happened later. Today, however, cannabis is used by millions as a form of medication and can be seen as something that helps to improve the quality of life of thousands of people. This post will aim to debunk the longstanding and unfortunate stigma and myths around cannabis due to various cultural and political reasons.

The first myth: Cannabis is highly addictive.

Cannabis is only…


Last week our team attended the Cannabis Europa conference in Madrid which has brought together investors, entrepreneurs, consultants, and other professionals in the emerging field of cannabis from Europe and North America. The conference explored conversations ranging from cultural aspects of cannabis consumption in Spain, current political stance towards legalization, and growing evidence base of medicinal benefits from the cannabis plant. Here in this blog post, we would like to share our three key takeaways from this conference.

1. The liberal attitude of Spain society towards cannabis

Spain is ranked 2-nd in Europe in terms of cannabis consumption with 11%…


Leafy Tunnel has been founded with the mission to back entrepreneurs who are aiming to maximise the potential of plant-based therapies providing relief from the pain, physical and mental stress and improving quality of life for both the person and their family. There are three main reasons for explaining our mission and investment thesis.

1) A Huge problem and unmet demand

More than 1 Billion people all over the world suffer from substance abuse, anxiety, post-traumatic stress, depression, and other mental illnesses. One in four people will suffer from neurological disorders at least once in their lives. 13.5 million deaths…


As a response to the current pandemic, regulators from all over the world have imposed restrictions almost on every industry predisposed to physical customer interaction. At the beginning of the quarantine period, some countries were initially hesitant to include cannabis stores in the list of essential services. This has left cannabis consumers with no other choice but to source their products from illicit channels. In the Netherlands, the Dutch cabinet originally ordered the cannabis stores to suspend operations but the government quickly reversed course after mayors warned that such a move would cause the illicit market to flourish. A similar…


There are two major categories of psychedelics that are being researched for their therapeutic value in the treatment of psychiatric disorders: Tryptamines and phenethylamines. More commonly known tryptamines include LSD, psilocybin (“magic mushrooms”), DMT, and Ibogaine. Mescaline and MDMA (“ecstasy”) are the most widely known psychedelics amongst phenethylamines. The first part of this blog post will explore the neuroscience of tryptamine psychedelics, its mechanism of action, and therapeutic potential.

The molecular structure of tryptamines including LSD, DMT, and psilocybin closely resemble the structure of neurotransmitter serotonin which plays a key role in mood regulation and social behavior. There are 14…

Leafy Tunnel

Leafy Tunnel is an early-stage venture capital firm investing in alternative medicine to address mental health and pain disorders.

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